I just did some brief research and the LD50 for intravenous ketamine is way lower than that. I’ve seen a lot of different numbers but anywhere from 50 to 150 milligrams per kilogram. Oral LD50s are much higher in the range you’re talking about.
Well 50-150mg/kg would be 4-12g for an 80kg adult. I dont think 10g is such a bad estimate. Ofc we cant know for sure because there are probably only a handful of ketamine deaths in humans. Estimates usually come from tests with rats or mice.
Oral being higher is kind of what I was saying with the lower bioavailability.
I just did some brief research and the LD50 for intravenous ketamine is way lower than that. I’ve seen a lot of different numbers but anywhere from 50 to 150 milligrams per kilogram. Oral LD50s are much higher in the range you’re talking about.
Well 50-150mg/kg would be 4-12g for an 80kg adult. I dont think 10g is such a bad estimate. Ofc we cant know for sure because there are probably only a handful of ketamine deaths in humans. Estimates usually come from tests with rats or mice.
Oral being higher is kind of what I was saying with the lower bioavailability.